3,4-Diiodobenzoic acid Basic Product Information

Product Name	3,4-Diiodobenzoic acid	CAS	35674-20-5
Synonyms	3,4-Diiodobenzoicacid;	Molecular Formula	C7H4I2O2
EINECS Number		Molecular Structure
Appearance	Light Yellow Powder
Purity
Supply Ability

3,4-Diiodobenzoic acid Quality documents

3,4-Diiodobenzoic acid Appearance/Package/Shipping/Storage

package

storage condition

Store in cool & dry place,Keep away from strong light and heat

3,4-Diiodobenzoic acid Application

3,4-Diiodobenzoic acid literature

Synthesis of highly efficient pH-sensitive DNA cleaving aminomethyl N-substituted cyclic enediyne and its L-lysine conjugate

Hatial, Ishita,Addy, Partha S.,Ghosh, Ananta K.,Basak, Amit

supporting information, p. 854 - 857 (2013/03/13)

Two 10-membered benzo-fused N-substituted cyclic enediynes, one an amino methyl and the other, a C-lysine conjugated derivative 2 and 3, respectively were synthesized (as a 1.2:1 mixture of regioisomers) and their DNA-cleavage efficiency studied. Both the compounds showed much better DNA-cleavage profile than that of the parent unsubstituted enediyne 1. The lysine conjugate 3 showed an efficient pH dependent cleavage to the extent of ～50% of linear DNA formation under ambient conditions.

Oxidative iodination of deactivated arenes in concentrated sulfuric acid with I₂/NaIO₄ and KI/NaIO₄ iodinating systems

Kraszkiewicz, Lukasz,Sosnowski, Maciej,Skulski, Lech

, p. 1195 - 1199 (2007/10/03)

Deactivated arenes were mono- or diiodinated with strong electrophilic I⁺ reagents, which were prepared from NaIO₄ and either I₂ or KI in concentrated H₂SO₄ (minimum 95% by weight). In general a small excess of the dark brown iodinating solution was used (1.1/1.5 equivalents, for nitrobenzene two equivalents was required). The iodinations were conducted at 25-30 °C with a reaction time of 1-2 hours using either a 'direct' or an 'inverse' method of aromatic iodination to give mono- or diiodinated pure products in 31-91% optimized yields. Georg Thieme Verlag Stuttgart.

Easy, inexpensive and effective oxidative iodination of deactivated arenes in sulfuric acid

Kraszkiewicz, Lukasz,Sosnowski, MacIej,Skulski, Lech

, p. 9113 - 9119 (2007/10/03)

Two 'model' deactivated arenes, benzoic acid and nitrobenzene, were effectively monoiodinated within 1 h at 25-30 °C, with strongly electrophilic I⁺ reagents, prior prepared from diiodine and various oxidants (CrO₃, KMnO₄, active MnO₂, HIO ₃, NaIO₃, or NaIO₄) in 90% (v/v) concd sulfuric acid (ca. 75 mol% H₂SO₄). Next, an I₂/ NaIO₃/90% (v/v) concd H₂SO₄ exemplary system was used to effectively mono- or diiodinate a number of deactivated arenes. All former papers dealing with the direct iodination of deactivated arenes are briefly reviewed.

3,4-Diiodobenzoic acid Upstream and downstream

35674-20-5 Upstream product

• 477534-94-4

  3,4-diiodo-benzaldehyde 

• 35674-29-4

  2-amino-4,5-diiodo-benzoic acid 

• 619-58-9

  4-iodobenzoic acid 

• 116529-62-5

  4-iodo-2-nitro benzoic acid 

• 20776-54-9

  2-amino-4-iodobenzoic acid 

• 101420-88-6

  4-iodo-3-nitrobenzaldehyde 

• 15164-44-0

  p-(iodophenyl)carboxaldehyde 

• 150-13-0

  4-amino-benzoic acid 

35674-20-5 Downstream Products

• 102014-49-3

  3,4-diiodo-benzoyl chloride 

• 1071750-65-6

  C₁₄H₁₈I₂O₅ 

• 1418218-93-5

  C₂₄H₃₁NO₅ 

• 1418218-67-3

  C₇H₆I₂O 

• 1418218-68-4

  C₈H₈I₂O₃S 

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