4-(hidroximetil)-5-metil-1,3-dioxol-2-ona Basic Product Information

Product Name	4-(hidroximetil)-5-metil-1,3-dioxol-2-ona	CAS	91526-18-0
Synonyms	4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one;	Molecular Formula	C5H6O4
EINECS Number	1308068-626-2	Molecular Structure
Appearance	Light Yellow Powder
Purity
Supply Ability

4-(hidroximetil)-5-metil-1,3-dioxol-2-ona Quality documents

4-(hidroximetil)-5-metil-1,3-dioxol-2-ona Appearance/Package/Shipping/Storage

package

storage condition

Store in cool & dry place,Keep away from strong light and heat

4-(hidroximetil)-5-metil-1,3-dioxol-2-ona Application

4-(hidroximetil)-5-metil-1,3-dioxol-2-ona literature

MONOETHYLENICALLY UNSATURATED MONOMERS AND USES THEREOF

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, (2021/06/22)

The invention relates to a monoethylenically unsaturated monomer of formula (I), and to the use thereof for producing a polymer. The invention also relates to the polymer obtained by polymerising said monomer, and to the use thereof in a composition for producing coatings.

Preparation method of olmesartan medoxomil key intermediate

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Paragraph 0026-0034, (2021/08/07)

The invention discloses a preparation method of an olmesartan medoxomil key intermediate, and belongs to the technical field of medicine synthesis. The key points of the technical scheme are as follows: triphosgene with relatively low toxicity is adopted to replace gaseous phosgene, so that the problems of storage and transportation are solved; and a molecular distillation technology is utilized to treat the crude product, so that the occurrence of a polymer at high temperature is avoided, and a high-yield product is obtained.

AN IMPROVED PROCESS FOR 4-(HYDROXYMETHYL)-5-METHYL-1,3-DIOXOL-2-ONE

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Page/Page column 5; 7-8, (2021/04/17)

The present invention relates to an improved process for 4-(Hydroxymethyl)-5-methyl-1,3-dioxol-2-one (I). The process involves reaction of compound of formula (II) with sodium acetate in presence of catalytic amount of potassium iodide in dimethyl formamide solvent at 25-30°C to give 5-methyl-2-oxo-1,3-dioxol-4-yl)methyl acetate (IV) which was further Acid hydrolysed by IPA. HCl in Isopropyl alcohol solvent to yield 4-(hydroxymethyl)-5-methyl-1,3-dioxol-2-one (I).

Method for synthesizing 4 - (hydroxymethyl) -5 - methyl-[1, 3] dioxole -2 - ketone (by machine translation)

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Paragraph 0009; 0022-0042, (2020/09/20)

The invention discloses a method for synthesizing 4 - (hydroxymethyl) -5 - methyl-[1, 3] dioxole -2 - ketone, and belongs to the technical field of chemical synthesis. The reaction equation in the synthesis process is as follows. By selecting proper solvent and hydrolysis medium and optimizing the dosage ratio between reactants, the reaction rate and yield are greatly improved, the reaction is more complete and thorough, the yield of the target product reaches 92%, and the purity of the target product reaches 97%. (by machine translation)

4-(hidroximetil)-5-metil-1,3-dioxol-2-ona Upstream and downstream

91526-18-0 Upstream product

• 91526-17-9

  4-formyloxymethyl-5-methyl-1,3-dioxolen-2-one 

• 80715-22-6

  4-bromomethyl-1,3-dioxa-5-methylcyclopentene-2-one 

• 37830-90-3

  4,5-Dimethyl-1,3-dioxole-2-one 

• 80841-78-7

  4-chloromethyl-5-methyl-1,3-dioxol-2-one 

91526-18-0 Downstream Products

• 173604-87-0

  (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 4-nitrophenyl carbonate 

• 863031-21-4

  Azilsartan medoxomil 

• 478297-09-5

  benzyl 1-{[((5-methyl-2-oxo-[1,3]dioxol-4-en-4-yl)methoxy)carbonyl]-aminomethyl}-1-cyclohexane-acetate 

• 912357-50-7

  (5-methyl-2-oxo-1,3-dioxol-4-yl)methyl 2-cyclopropyl-1-{[2'-(5-oxo-4,5-dihydro-1,2,4-oxadiazol-3-yl)biphenyl-4-yl]methyl}-1H-benzimidazole-7-carboxylate 

• 1121795-67-2

  S-ethyl O-((5-methyl-2-oxo-1,3-dioxol-4-yl)methyl) carbonothioate 

• 1159501-38-8

  4-((R)-3-(bis(5-methyl-2-oxo-[1,3]dioxol-4-ylmethoxy)phosphoryl)-2-((6-((S)-3-methoxypyrrolidin-1-yl)-2-phenylpyrimidine-4-carbonyl)amino)propionyl)piperazine-1-carboxylic acid butyl ester 

• 1309361-34-9

  (2S)-2-(5-methyl-1,3-dioxol-2-one-4-ylmethylamino)-2-phenyl-n-butyl-3,4,5-trimethoxybenzoate 

• 1394049-42-3

  (2S,4R)-5-biphenyl-4-yl-2-hydroxymethyl-2-methyl-4-[(3H-[1,2,3]triazole-4-carbonyl)-amino]-pentanoic acid 5-methyl-2-oxo-[1,3]dioxol-4-ylmethyl ester 

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